Statistics Summary Report for SGC Center

Last updated: Feb 2 2012

Target Status Statistics

Table 1: Status Statistics for SGC
Table 2: Status Statistics for SGC by Organisms

Sequence Redundancy Statistics

Table 3: Sequence Redundancy Statistics for SGC by Experimental Status

Target Status Statistics

Total number of targets deposited by SGC to TargetDB: 107

View SGC Target List

Table 1: Status Statistics for SGC

Status	Total Number of Targets	(%) Relative to "Cloned" Targets	(%) Relative to "Expressed" Targets	(%) Relative to "Purified" Targets	(%) Relative to "Crystallized" Targets
Cloned	107	100.0	-	-	-
Expressed	98	91.6	100.0	-	-
Soluble	61	57.0	62.2	-	-
Purified	47	43.9	48.0	100.0	-
Crystallized	18	16.8	18.4	38.3	100.0
Diffraction-quality Crystals	2	1.9	2.0	4.3	11.1
Diffraction	0	0.0	0.0	0.0	0.0
NMR Assigned	0	0.0	0.0	0.0	-
HSQC	0	0.0	0.0	0.0	-
Crystal Structure	0	0.0	0.0	0.0	0.0
NMR Structure	0	0.0	0.0	0.0	-
In PDB1	0	0.0	0.0	0.0	0
Work Stopped	0	-	-	-	-
Test Target	0	-	-	-	-
Other	0	-	-	-	-

Last updated: Feb 2 2012

Note 1: Number of targets with status "in PDB" may not be equal to number of structures determined by a project. A target may reference several PDB IDs (example: structure of the same polypeptides with different ligands). Multiple targets in TargetDB may identify the same PDB structure when a stucture is a result of collaboration between different centers and each center includes the target on its target list.

Table 2: Status Statistics for SGC by Organism

These statistics are derived from mapping of target sequences to GenBank using >=98% sequence identity cut off.

Organism	Total Number1	Work Stopped	Cloned	Expressed	Purified	Crystallized	Crystal Structure	NMR Structure	In PDB
Bacteria	14	0	14	14	14	3	0	0	0
Prokaryota	14	0	14	14	14	3	0	0	0
Mouse	19	0	19	14	6	5	0	0	0
Human	92	0	92	83	33	15	0	0	0
Eukaryota	92	0	92	83	33	15	0	0	0

Last updated: Feb 2 2012

Note 1: Total counts in this table may differ from total number of targets and structures. A target is counted in different organism specifications if:
- a target is mapped to different organisms
- a target is a hybrid complex (for example:a complex of human and mouse polypeptides).

Sequence Redundancy Statistics

Table 3: Sequence Redundancy Statistics for SGC by Experimental Status

Sequence Identity(%)	Novel Targets Status: Selected	Novel Targets Status: Cloned	Novel Targets Status: Expressed	Novel Targets Status: Purified	Novel Targets Status: Crystallized	Novel Targets Status: Crystal Structure	Novel Targets Status: in PDB
<100	107	107	98	47	18	0	0
<98	107	107	98	47	18	0	0
<95	106	106	98	47	18	0	0
<90	106	106	98	47	18	0	0
<70	103	103	95	46	18	0	0
<50	96	96	92	43	18	0	0
<40	77	82	79	42	18	0	0
<30	32	49	54	34	17	0	0

Last updated: 12-01-10

Sequence redundancy is calculated by clustering analysis using BLASTClust program with similarity threshold set to percent of sequence identity. Please view detailed explanation of sequence redundancy calculations and BLASTClust threshold settings. Sequence redundancy calculations are based on comparison to all protein sequences in TargetDB which are in the same experimental status category and at least 20 amino acids long.